TOPOLOGICAL DATA ANALYSIS AS A MORPHOMETRIC METHOD: USING PERSISTENT HOMOLOGY TO DEMARCATE A LEAF MORPHOSPACE

Topological Data Analysis as a Morphometric Method: Using Persistent Homology to Demarcate a Leaf Morphospace

Current morphometric methods that comprehensively measure shape cannot compare the disparate leaf shapes found in seed plants and are sensitive to processing artifacts.We explore the use of persistent homology, a topological method applied as a filtration across simplicial complexes (or more simply, a method to measure topological features of space

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High IRF8 expression correlates with CD8 T cell infiltration and is a predictive biomarker of therapy response in ER-negative breast cancer

Abstract Background Characterization of breast cancer (BC) through the determination of conventional markers such as ER, PR, HER2, and Ki67 has been useful as a predictive and therapeutic tool.Also, assessment of tumor-infiltrating lymphocytes has been proposed as an important prognostic aspect to be considered in certain BC subtypes.However, there

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Spatial distribution of preantral follicles in the equine ovary.

Comprehensive studies on spatial distribution of preantral follicles in the ovary are scarce.Considering that preantral follicles represent the main ovarian reserve, harvesting of these follicles is crucial for the development/use of assisted reproductive techniques.Therefore, knowledge on follicle spatial distribution can be helpful for targeting

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